Iron Metabolism in Cancer
— Read on www.ncbi.nlm.nih.gov/pmc/articles/PMC6337236/
Category: Parential Alienation-Child Abuse
A standardized herbal extract mitigates tumor inflammation and augments chemotherapy effect of docetaxel in prostate cancer | Scientific Reports
Activation of the NFκB pathway is often associated with advanced cancer and has thus been regarded as a rational therapeutic target. Wedelia chinensis is rich in luteolin, apigenin, and wedelolactone that act synergistically to suppress androgen receptor activity in prostate cancer. Interestingly, our evaluation of a standardized Wedelia chinensis herbal extract (WCE) concluded its efficacy on hormone-refractory prostate cancer through systemic mechanisms. Oral administration of WCE significantly attenuated tumor growth and metastasis in orthotopic PC-3 and DU145 xenografts. Genome-wide transcriptome analysis of these tumors revealed that WCE suppressed the expression of IKKα/β phosphorylation and downstream cytokines/chemokines, e.g., IL6, CXCL1, and CXCL8. Through restraining the cytokines expression, WCE reduced tumor-elicited infiltration of myeloid-derived suppressor cells (MDSCs), tumor-associated macrophages (TAMs) and endothelial cells into the tumors, therefore inhibiting angiogenesis, tumor growth, and metastasis. In MDSCs, WCE also reduced STAT3 activation, downregulated S100A8 expression and prevented their expansion. Use of WCE in combination with docetaxel significantly suppressed docetaxel-induced NFκB activation, boosted the therapeutic effect and reduced the systemic toxicity caused by docetaxel monotherapy. These data suggest that a standardized preparation of Wedelia chinensis extract improved prostate cancer therapy through immunomodulation and has potential application as an adjuvant agent for castration-resistant prostate cancer.
— Read on www.nature.com/articles/s41598-017-15934-0
A Review of the Potential of Phytochemicals from Prunus africana (Hook f.) Kalkman Stem Bark for Chemoprevention and Chemotherapy of Prostate Cancer
A Review of the Potential of Phytochemicals from Prunus africana (Hook f.) Kalkman Stem Bark for Chemoprevention and Chemotherapy of Prostate Cancer
— Read on www.hindawi.com/journals/ecam/2017/3014019/
The medications that change who we are – BBC Future
I can and certainly intend to expand on the toxicity and acceptance
of this inducement of illness , especially mental illness and then heap
more guilt and shame, ignoring abuses , and trauma etc .
No one heard me , medicated I had no rights as the projections
heaped towards my at fault . No one has heard me since , for the same
reasons I’m supposed to be shut up …
The side effects go way beyond reported even here .. #ErasingFamliesForProfit
©️
Blessings & Peace ,
Doña Luna
They’ve been linked to road rage, pathological gambling, and complicated acts of fraud. It turns out many ordinary medications don’t just affect our bodies – they affect our brains.
— Read on www.bbc.com/future/article/20200108-the-medications-that-change-who-we-are
Screentime Is Making Kids Moody, Crazy, and Lazy | Psychology Today
The rapid , high speed of games teaches the world is that frenzied .
So very glad , folks are waking to slowing things down for kiddies
and adults alike , simpler is so much healthier …I still adore the Walton’s
Family shows ..I don’t regret not living the Dallas or Dynasty show
that mask so many …greed is so unattractive and teaches nothing
positive .
©️
Blessings & Peace
Doña Luna
By disrupting sleep, suppressing the brain’s frontal lobe, raising stress hormones, and fracturing attention, daily screen-time harms children.
— Read on www.psychologytoday.com/us/blog/mental-wealth/201508/screentime-is-making-kids-moody-crazy-and-lazy
Delusional Belief in the Child -Craig / 71995.51 Child Psychological Abuse
In the aftermath , I was kinda allowed to know the
success of our granddaughter’s being , and my determination
to successfully conclude the old business . Clarity , in most
failures and negatives being associated with me..
It’s with a much lighter heart , after 7 years of having the
verification , my heart healing , and reeling as this epidemic
of child abuse escalates , many and mighty WE stand , and
say no more .
Atlantic Abyss Quake
Newborn Dies of Sepsis 2 Months After Vitamin K Shot
The most horrific outcome , totally preventable , the predictable
blame of authorities against the parents ..
A healthy infant dies of sepsis 2 months after receiving the Vitamin K shot. “I got a call from my husband that tore my world apart.”
— Read on www.stopmandatoryvaccination.com/parent/vaccine-injury/newborn-dies-of-sepsis-2-months-after-vitamin-k-shot/
Childress On Persecutory Delusion :A “creation” of the allied parent
You’ll hear me talk a lot about the persecutory delusion, the child’s false belief in “victimization,” created by the allied parent, and how that’s the encapsulated (limited-scope) persecutory delusion of the allied parent, your ex- toward you, that is then being imposed on the child – a shared persecutory delusion with the parent as the “primary case.”
A shared persecutory delusion is an ICD-10 diagnosis of F24 Shared Psychotic Disorder, that’s what a shared delusional disorder is called, a Shared Psychotic Disorder.
The ICD-10 diagnostic system is used throughout the world, it’s a coding system for all medical and psychiatric disorders, it’s used in the U.S. for all insurance billing, medical and psychological, the ICD-10 code is what’s used for billing insurance.
The ICD-10 diagnosis for a shared persecutory delusion between a parent and child, with the parent as the “primary case” is an ICD-10 diagnosis of F24 Shared Psychotic Disorder.
The descriptions for the disorders listed in the ICD-10, like cancer, or depression, or any medical or psychiatric disorder, are pretty brief. It’s mostly just the category system for ALL medical and psychiatric diagnoses, it doesn’t go into a lot of depth explaining each medical and psychiatric disorder.
For psychiatric disorders, the American Psychiatric Association is who you want to turn to for a description of the pathology. The American Psychiatric Association offers a pretty full description of a Shared Psychotic Disorder, let me run through it for a second.
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From the American Psychiatric Association:
“The essential features of Shared Psychotic Disorder (Folie a Deux) is a delusion that develops in an individual who is involved in a close relationship with another person (sometimes termed the “inducer” or “the primary case”) who already has a Psychotic Disorder with prominent delusions (Criteria A).” (p. 332)
Dr. Childress: note the two terms for the allied parent, the “inducer” of the child’s delusion (the child’s rigidly held and false belief in supposed “victimization”) and the “primary case” of the shared persecutory delusion, you’ll hear me use those two interchangeably.
“Usually the primary case in Shared Psychotic Disorder is dominant in the relationship and gradually imposes the delusional system on the more passive and initially healthy second person.”
Dr. Childress Comment: This contains two key elements, the first is the power, domination, and influence the allied parent has on the child, and then gradually “imposing the delusional system” on the child, “the more passive and initially healthy second person.”
“Individuals who come to share delusional beliefs are often related by blood or marriage and have lived together for a long time, sometimes in relative isolation.”
Dr. Childress Comment: The parent and child are related by blood, this feature definitely applies.
“If the relationship with the primary case is interrupted, the delusional beliefs of the other individual usually diminish or disappear.”
Dr. Childress: Here, the APA gives direct treatment guidance, i.e., interrupt the relationship with the “primary case” – the “inducer” of the child’s persecutory delusions.
“Although most commonly seen in relationships of only two people, Shared Psychotic Disorder can occur in larger number of individuals, especially in family situations in which the parent is the primary case and the children, sometimes to varying degrees, adopt the parent’s delusional beliefs.”
Dr. Childress Comment: The final part of that description is EXACTLY this pathology, it is a family situation in which the “parent is the primary case” and the children, to varying degrees, “adopt the parent’s delusional beliefs.”
Exactly. An encapsulated persecutory delusion imposed on the child by the “primary case” – the “inducer” – of the persecutory delusion. Here is the definition of a persecutory delusion from the American Psychiatric Association:
“Persecutory Type: delusions that the person (or someone to whom the person is close) is being malevolently treated in some way.”
The American Psychiatric Association also describes additional features of a Shared Psychotic Disorder.
Associated Features and Disorders
“Aside from the delusional beliefs, behavior is usually not otherwise odd or unusual in Shared Psychotic Disorder. Impairment is often less severe in individuals with Shared Psychotic Disorder than in the primary case.”
Dr. Childress Comment: the child goes to school, the allied parent goes to work, “aside from the delusional beliefs,” the shared persecutory delusion relative to the targeted parent, their “behavior is not otherwise odd or unusual.”
Prevalence
“Little systematic information about the prevalence of Shared Psychotic Disorder is available. This disorder is rare in clinical settings, although it has been argued that some cases go unrecognized.”
Dr. Childress Comment: Yes, like here, it is going “unrecognized” here.
Course
“Without intervention, the course is usually chronic, because this disorder most commonly occurs in relationships that are long-standing and resistant to change. With separation from the primary case, the individual’s delusional beliefs disappear, sometimes quickly and sometimes quite slowly.”
Dr. Childress Comment: These are two incredibly important points. If we do not “interrupt the relationship with the primary case” then the situation continues to get worse, it’s chronic, it does not self-improve over time, it keeps getting worse and worse as long as the child is in contact with the “primary case” – the “inducer” – of the child’s persecutory delusion.
Dr. Childress, Comment: If, however, we separate the child from the primary case of the persecutory delusion, the allied parent, then the child’s “delusional beliefs will disappear,” “sometimes quickly” (High Road workshop augmented recovery), “sometimes quite slowly” (psychotherapy or no treatment).
—————
That is my diagnosis for this pathology, an encapsulated shared persecutory delusion, with the parent as the primary case – the “inducer” – who “gradually imposes the delusional system” on the child, “the more passive and initially healthy second person.” American Psychiatric Association; ICD-10 F24 Shared Psychotic Disorder.
Go argue with the American Psychiatric Association and the ICD-10, it’s them that says it, not me. If it fits, I sits.
Craig Childress, Psy.D.
Clinical Psychologist, PSY 18857
